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    NRAS p.Q61R Reference StandardEnquiry

    Product Description

    Product database

    Format Genomic DNA
    Description NRAS Q61R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61R results in a loss of Nras GTPase function as indicated by increased GTP-bound Nras, which leads to activation of Mapk signaling in culture (PMID: 16818621).
    Technical Data
    DNA Change c.182A>G
    AA Change p.Q61R
    Mutation type Substitution - Missense
    Zygosity Homozygous
    Allelic Frequency 100%
    Transcript ENST00000369535
    Cosmic ID COSM584
    Chr position(GRCh37) chr1:115256529
    Buffer Tris-EDTA
    Product Information
    Intended Use Research Use Only
    Unit Size 1ug
    Concentration Download for COA
    Purofication Download for COA
    DNA electrophoresis Download for COA
    Sanger sequencing
    Storage 4℃
    Expiry 36 months from the date of manufacture

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